Genotipia › Foros › Actualidad › Noticias del día
Etiquetado: 23 de octubre de 2019
- Este debate tiene 117 respuestas, 2 mensajes y ha sido actualizado por última vez el hace 1 año, 3 meses por
Genotipia.
-
AutorEntradas
-
mayo 21, 2019 a las 8:44 am #29272
GenotipiaSuperadministradorNOTICIAS DEL MARTES 21 DE MAYO DE 2019
Investigación original: Imel EA, et al. Burosumab versus conventional therapy in children with X-linked hypophosphataemia: a randomised, active-controlled, open-label, phase 3 trial. The Lancet. 2019. Doi: https://doi.org/10.1016/S0140-6736(19)30654-3
Investigación original: Jiang SH, et al. Functional rare and low frequency variants in BLK and BANK1 contribute to human lupus. Nat comm. 2019. Doi: https://doi.org/10.1038/s41467-019-10242-9
NeoMutate: una herramienta bioinformática para la predicción de mutaciones somáticas en cáncer.
Investigación original: Anzar I, et al. NeoMutate: an ensemble machine learning framework for the prediction of somatic mutations in cancer. BMC Med Genomics. 2019. Doi: https://doi.org/10.1186/s12920-019-0508-5
Investigación original: Tornabene P, et al. Intein-mediated protein trans-splicing expands adeno-associated virus transfer capacity in the retina. Sci Transl Med. 2019. Doi: http://dx.doi.org/10.1126/scitranslmed.aav4523
mayo 22, 2019 a las 8:19 am #29289GenotipiaSuperadministradorNOTICIAS DEL MIÉRCOLES 22 DE MAYO DE 2019
Investigación original: Fine RS, et al. Benchmarker: An Unbiased, Association-Data-Driven Strategy to Evaluate Gene Prioritization Algorithms. Am J Hum Gen. 2019. Doi: https://doi.org/10.1016/j.ajhg.2019.03.027
Fuente: After GWAS studies, how to narrow the search for genes? http://discoveries.childrenshospital.org/gwas-benchmarker/
Investigación original: Singh A, et al. Familial Hypercholesterolemia Among Young Adults With Myocardial Infarction. J Am C Cardio. 2019. Doi: https://doi.org/10.1016/j.jacc.2019.02.059
Una revisión del papel de los macrófagos en la resolución de la inflamación.
Investigación original: Watanabe S, et al. The role of macrophages in the resolution of inflammation. JCI. 2019. Doi: https://doi.org/10.1172/JCI124615
Investigación original: Border R, et al. No Support for Historical Candidate Gene or Candidate Gene-by-Interaction Hypotheses for Major Depression Across Multiple Large Samples. Am J Psych. 2019. Doi: https://doi.org/10.1176/appi.ajp.2018.18070881
Editorial: Bien SA y Peters U. Moving from one to many: insights from the growing list of pleiotropic cancer risk genes. Brit J Cancer. 2019. Doi: https://doi.org/10.1038/s41416-019-0475-9
mayo 23, 2019 a las 9:10 am #29328GenotipiaSuperadministradorNOTICIAS DEL JUEVES 23 DE MAYO DE 2019
Investigación: Li P, et al. Epigenetic dysregulation of enhancers in neurons is associated with Alzheimer’s disease pathology and cognitive symptoms. Nat Comm. 2018. Doi: https://doi.org/10.1038/s41467-019-10101-7
Investigación original: Chan CWY, et al. Impact of cancer mutational signatures on transcription factor motifs in the human genome. BMC Med Gen. 2019. Doi: https://doi.org/10.1186/s12920-019-0525-4
Investigación original: Kurozumi S, et al. A key genomic subtype associated with lymphovascular invasion in invasive breast cancer. Brit J Cancer. 2019. Doi: https://doi.org/10.1038/s41416-019-0486-6
Investigación original: Flannick J, et al. Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls. Nature. 2019. Doi: https://doi.org/10.1038/s41586-019-1231-2
Fuente: Massive sequencing study links rare DNA alterations to type 2 diabetes. https://www.broadinstitute.org/news/massive-sequencing-study-links-rare-dna-alterations-type-2-diabetes
Investigación original: Ling YH, et al. Point centromere activity requires an optimal level of centromeric noncoding RNA. Proc Nat Ac Sci. 2019. Doi: https://doi.org/10.1073/pnas.1821384116
Fuente: HKU biologists discover cell division requires a balanced level of non-coding RNA for chromosome stability. https://www.hku.hk/press/news_detail_19432.html
mayo 24, 2019 a las 8:47 am #29333GenotipiaSuperadministradorNOTICIAS DEL VIERNES 24 DE MAYO DE 2019
Investigación original: Toomer KA, et al. Primary cilia defects causing mitral valve prolapse. Sci Transl Med. 2019. Doi: http://dx.doi.org/10.1126/scitranslmed.aax0290
Investigación original: Pearson S, et al. Loss of TLE3 promotes the mitochondrial program in beige adipocytes and improves glucose metabolism. Genes & Dev. 2019. Doi: http://dx.doi.org/10.1101/gad.321059.118
Identificada una nueva ruta molecular de acción de la rapamicina.
Investigación original: Zhang X, et al. Rapamycin directly activates lysosomal mucolipin TRP channels independent of mTOR. PLOS Biology. 2019. Doi: https://doi.org/10.1371/journal.pbio.3000252
Investigación original: Tobin MK, et al. Human Hippocampal Neurogenesis Persists in Aged Adults and Alzheimer’s Disease Patients. Cell Stem Cell. 2019. Doi: https://doi.org/10.1016/j.stem.2019.05.003
Investigación original: Xu R, et al. OLIG2 Drives Abnormal Neurodevelopmental Phenotypes in Human iPSC-Based Organoid and Chimeric Mouse Models of Down Syndrome. Cell Stem Cell. 2019. Doi: https://doi.org/10.1016/j.stem.2019.04.014
Fuente: Targeting Key Gene Could Help Lead to Down Syndrome Treatment. https://news.rutgers.edu/targeting-key-gene-could-help-lead-down-syndrome-treatment/20190514#.XOelpqS-nct
mayo 28, 2019 a las 8:33 am #29368GenotipiaSuperadministradorNOTICIAS DEL MARTES 28 DE MAYO DE 2019
Investigación original: Sagi-Dain L, et al. Chromosomal microarray vs. NIPS: analysis of 5541 low-risk pregnancies. Gen Med. 2019. Doi: https://doi.org/10.1038/s41436-019-0550-x
Mutaciones en el gen RRAS2 pueden producir síndrome de Noonan.
Investigación original:
Niihori T, et al. Germline-Activating RRAS2 Mutations Cause Noonan Syndrome. Am J Hum Gen. 2019. Doi: https://doi.org/10.1016/j.ajhg.2019.04.014
Capri Y, et al. Activating Mutations of RRAS2 Are a Rare Cause of Noonan Syndrome. Am J Hum Gen. 2019. Doi: https://doi.org/10.1016/j.ajhg.2019.04.013
Investigación original: Milko LV, et al. An Age-Based Framework for Evaluating Genome-Scale Sequencing Results in Newborn Screening. J Ped. 2019. Doi: https://doi.org/10.1016/j.jpeds.2018.12.027
Fuente: If You Could Learn Every Disease Your Child Could Possibly Develop in Life, Would You? http://news.unchealthcare.org/news/2019/may/if-you-could-learn-every-disease-your-child-could-possibly-develop-in-life-would-you
Investigación original: Shahbazi R, et al. Targeted homology-directed repair in blood stem and progenitor cells with CRISPR nanoformulations. Nat Mat. 2019. Doi: https://doi.org/10.1038/s41563-019-0385-5
Fuente: Could gold be the key to making gene therapy for HIV, blood disorders more accessible? https://www.eurekalert.org/pub_releases/2019-05/fhcr-cgb052219.php
La FDA aprueba una nueva terapia génica para pacientes pediátricos con atrofia muscular espinal.
Nota de prensa: FDA approves innovative gene therapy to treat pediatric patients with spinal muscular atrophy, a rare disease and leading genetic cause of infant mortality. https://www.fda.gov/news-events/press-announcements/fda-approves-innovative-gene-therapy-treat-pediatric-patients-spinal-muscular-atrophy-rare-disease
Investigación original: Zhou J, et al. Whole-genome deep-learning analysis identifies contribution of noncoding mutations to autism risk. Nat Gen. 2019. Doi: https://doi.org/10.1038/s41588-019-0420-0
mayo 29, 2019 a las 9:26 am #29409GenotipiaSuperadministradorNOTICIAS DEL MIÉRCOLES 29 DE MAYO DE 2019
Investigación original: Wei W, et al. Germline selection shapes human mitochondrial DNA diversity. Science. 2019. Doi: http://dx.doi.org/10.1126/science.aau6520
Fuente: Interplay between mitochondria and the nucleus may have implications for changing cell’s ‘batteries’. https://www.cam.ac.uk/research/news/interplay-between-mitochondria-and-the-nucleus-may-have-implications-for-changing-cells-batteries
Utilidad clínica de paneles de diagnóstico de diseño en tumores pediátricos.
Investigación original: Surrey LF, et al. Clinical utility of custom-designed NGS panel testing in pediatric tumors. Genome Medicine. 2019. Doi: https://doi.org/10.1186/s13073-019-0644-8
Investigación original: Davies MR, et al. Atlas of group A streptococcal vaccine candidates compiled using large-scale comparative genomics. Nat Gen. 2019. Doi: https://doi.org/10.1038/s41588-019-0417-8
Investigación original: Pietilä M, et al. SORLA regulates endosomal trafficking and oncogenic fitness of HER2. Nat Comm. 2019. Doi: https://doi.org/10.1038/s41467-019-10275-0
Fuente: Researchers from Turku Bioscience Centre Identified Novel Oncogenic Function for Receptor Linked with Alzheimer’s Disease. https://www.utu.fi/en/news/press-release/researchers-from-turku-bioscience-centre-identified-novel-oncogenic-function
Investigación original: Gelernter J, et al. Genome-wide Association Study of Maximum Habitual Alcohol Intake in >140,000 U.S. European and African American Veterans Yields Novel Risk Loci. Biological Psychiatry, 2019; DOI: http://dx.doi.org/10.1016/j.biopsych.2019.03.984
Investigación original: Zeitz MJ, et al. Dynamic UTR Usage Regulates Alternative Translation to Modulate Gap Junction Formation during Stress and Aging. Cell Reports. 2019. Doi: https://doi.org/10.1016/j.celrep.2019.04.114
mayo 30, 2019 a las 8:54 am #29421GenotipiaSuperadministradorInvestigación original: Hijmans JG, et al. Insufficient sleep is associated with a pro‐atherogenic circulating microRNA signature. Exp Phys. 2019. Doi: https://doi.org/10.1113/EP087469
El gen SMAD6 aparece mutado con frecuencia en la sinostosis radioulnar no sindrómica.
Investigación original: Yang Y, et al. SMAD6 is frequently mutated in nonsyndromic radioulnar synostosis. Gen Med. 2019. Doi: https://doi.org/10.1038/s41436-019-0552-8
Artículo original: Mikhail FM, et al. Technical laboratory standards for interpretation and reporting of acquired copy-number abnormalities and copy-neutral loss of heterozygosity in neoplastic disorders: a joint consensus recommendation from the American College of Medical Genetics and Genomics (ACMG) and the Cancer Genomics Consortium (CGC). Gen Med. 2019. Doi: https://doi.org/10.1038/s41436-019-0545-7
Investigación original: Cristiano S, et al. Genome-wide cell-free DNA fragmentation in patients with cancer. Nature. 2019. Doi: https://doi.org/10.1093/molbev/msz077
Fuente: Johns Hopkins Researchers Design New Blood Test That Uses DNA ‘Packaging’ Patterns to Detect Multiple Cancer Types. https://www.hopkinsmedicine.org/news/newsroom/news-releases/johns-hopkins-researchers-design-new-blood-test-that-uses-dna-packaging-patterns-to-detect-multiple-cancer-types
Un estudio revela una conexión entre el metabolismo del folato y la proteína epigenética BRD4.
Investigación original: Sdelci S, et al. MTHFD1 interaction with BRD4 links folate metabolism to transcriptional regulation. Nat Genet . 2019. DOI: http://dx.doi.org/10.1038/s41588-019-0413-z
Investigación original: Barfield R, et al. Epigenome-wide association analysis of daytime sleepiness in the Multi-Ethnic Study of Atherosclerosis reveals African-American-specific associations. Sleep. 2019. Doi: https://doi.org/10.1093/
mayo 31, 2019 a las 8:35 am #29510GenotipiaSuperadministradorNOTICIAS DEL VIERNES 31 DE MAYO DE 2019
Investigación original: Pisciottano F, et al. Inner Ear Genes Underwent Positive Selection and Adaptation in the Mammalian Lineage. Mol Bio Evo. 2019. Doi: https://doi.org/10.1093/molbev/msz077
Investigación original: Mishima H, et al. Evaluation of Face2Gene using facial images of patients with congenital dysmorphic syndromes recruited in Japan. J Hum Gen. 2019. Doi: https://doi.org/10.1038/s10038-019-0619-z
Ciertas mutaciones en el tejido hepático pueden mejorar su capacidad de regeneración.
Investigación original: Zhu M, et al. Somatic Mutations Increase Hepatic Clonal Fitness and Regeneration in Chronic Liver Disease. Cell. 2019 Apr 18;177(3):608-621.e12. doi: http://dx.doi.org/10.1016/j.cell.2019.03.026
Investigación original: Gifford CA, et al. Oligogenic inheritance of a human heart disease involving a genetic modifier. Science. 2019. Doi: http://dx.doi.org/10.1126/science.aat5056
Fuente: Combination of Three Gene Mutations Results in Deadly Human Heart Disease. https://gladstone.org/about-us/press-releases/combination-three-gene-mutations-results-deadly-human-heart-disease
Investigación original: Matsumoto S, et al. DNA damage detection in nucleosomes involves DNA register shifting. Nature. 2019. Doi: https://doi.org/10.1038/s41586-019-1259-3
Fuente: A new mechanism for accessing damaged DNA. https://www.fmi.ch/news/releases/articles/?news=409
junio 3, 2019 a las 9:04 am #29522
Amparo Tolosa (Coordinadora de Contenido Editorial)SuperadministradorNOTICIAS DEL LUNES 3 DE JUNIO DE 2019
Investigación original: Wu CC, et al. Paternal Tobacco Smoke Correlated to Offspring Asthma and Prenatal Epigenetic Programming. Frontiers Genetics. 2019. https://doi.org/10.3389/fgene.2019.00471
Un estudio evalúa la regulación de la memoria asociada al estrés por parte de los microARNs.
Investigación original: Sillivan SE, et al. MicroRNA regulation of persistent stress-enhanced memory. Mol Psych. 2019. Doi: https://doi.org/10.1038/s41380-019-0432-2
Investigación original: Wuttke M, et al. A catalog of genetic loci associated with kidney function from analyses of a million individuals. Nat Gen. 2019. Doi: https://doi.org/10.1038/s41588-019-0407-x
El análisis de la cromatina revela diferentes estados en el cáncer de mama.
Investigación original: Grosselin K, et al. High-throughput single-cell ChIP-seq identifies heterogeneity of chromatin states in breast cancer. Nat Gen. 2019. Doi: https://doi.org/10.1038/s41588-019-0424-9
Variantes genéticas en el gen MED12L producen discapacidad intelectual.
Investigación original: Nizon M, et al. Variants in MED12L, encoding a subunit of the mediator kinase module, are responsible for intellectual disability associated with transcriptional defect. Gen Med. 2019. Doi: https://doi.org/10.1038/s41436-019-0557-3
junio 4, 2019 a las 9:02 am #29554GenotipiaSuperadministradorNOTICIAS DEL MARTES 4 DE JUNIO DE 2019
Un atlas genómico de variación epigenética en humanos.
Investigación original: Gunasekara CJ, et al. A genomic atlas of systemic interindividual epigenetic variation in humans. Genome Biology. 2019. Doi: https://doi.org/10.1186/s13059-019-1708-1
Investigación original: June-Koo Lee J, et al. Tracing Oncogene Rearrangements in the Mutational History of Lung Adenocarcinoma. Cell. 2019. Doi: https://doi.org/10.1016/j.cell.2019.05.013
Investigación original: Hosie S, et al. Gastrointestinal dysfunction in patients and mice expressing the autism‐associated R451C mutation in neuroligin‐3. Autism Res. 2019. Doi: https://doi.org/10.1002/aur.2127
Investigación original: Park SH, et al. Highly efficient editing of the β-globin gene in patient-derived hematopoietic stem and progenitor cells to treat sickle cell disease. Nuc Ac Res. 2019. Doi: https://doi.org/10.1093/nar/gkz475
Fuente: New genetic weapons challenge sickle cell disease. https://news.rice.edu/2019/06/03/new-genetic-weapons-challenge-sickle-cell-disease-2/
Investigación original: Wei X y Nielsen R. CCR5-∆32 is deleterious in the homozygous state in humans. Nat Med. 2019. Doi: https://doi.org/10.1038/s41591-019-0459-6
Fuente: CRISPR baby mutation significantly increases mortality. https://news.berkeley.edu/2019/06/03/crispr-baby-mutation-significantly-increases-mortality/
junio 5, 2019 a las 8:31 am #29581GenotipiaSuperadministradorNOTICIAS DEL MIÉRCOLES 5 DE JUNIO DE 2019
Investigación original: Eigenbrod O, et al. Rapid molecular evolution of pain insensitivity in multiple African rodents. Science. 2019. Doi: http://dx.doi.org/10.1126/science.aau0236
Investigación original: Fumagalli M, et al. Genetic diversity of CHC22 clathrin impacts its function in glucose metabolism. eLife. 2019. Doi: https://doi.org/10.7554/eLife.41517
Fuente: Gene mutation evolved to cope with modern high-sugar diets. https://www.eurekalert.org/pub_releases/2019-06/ucl-gme060319.php
Investigación original: Guo X, et al. Genetic and genomic alterations differentially dictate low-grade glioma growth through cancer stem cell–specific chemokine recruitment of T cells and microglia. Neuro-Oncology. 2019. Doi: https://doi.org/10.1093/neuonc/noz080
Un comentario sobre posibles estrategias para llevar a cabo terapia génica en línea germinal.
Comentario: Wolf DP, et al. Principles of and strategies for germline gene therapy. Nat Med. 2019. Doi: https://doi.org/10.1038/s41591-019-0473-8
Identificación de genes relacionados con enfermedades raras a partir del análisis de ARN en sangre.
Investigación original: Frésard L, et al. Identification of rare-disease genes using blood transcriptome sequencing and large control cohorts. Nat Med. 2019. Doi: https://doi.org/10.1038/s41591-019-0457-8
Una revisión sobre los últimos avances en reparación de la médula espinal.
Revisión: Courtine G y Sofroniew MV. Spinal cord repair: advances in biology and technology. Nat Med. 2019. Doi: https://doi.org/10.1038/s41591-019-0475-6
junio 6, 2019 a las 8:57 am #29606GenotipiaSuperadministradorNOTICIAS DEL JUEVES 6 DE JUNIO DE 2019
Investigación original: Terré B,e t al. Defects in efferent duct multiciliogenesis underlie male infertility in GEMC1-, MCIDAS- or CCNO-deficient mice. Development. 2019. Doi: http://dx.doi.org/10.1242/dev.162628
Investigación original: Mundorf J, et al. Ets21c Governs Tissue Renewal, Stress Tolerance, and Aging in the Drosophila Intestine. Cell Reports. 2019. Doi: https://doi.org/10.1016/j.celrep.2019.05.025
Análisis de imagen para mejorar el diagnóstico mediante secuenciación de exomas.
Investigación original: Hsieh TC, et al. PEDIA: prioritization of exome data by image analysis. Gen Med. 2019. Doi: https://doi.org/10.1038/s41436-019-0566-2
Investigación original: Burke W, et al. Improving recommendations for genomic medicine: building an evolutionary process from clinical practice advisory documents to guidelines. Gen Med. 2019. Doi: https://doi.org/10.1038/s41436-019-0549-3
Investigación original: Mullins N, et al. GWAS of Suicide Attempt in Psychiatric Disorders and Association With Major Depression Polygenic Risk Scores. Am J Psych. 2019. Doi: https://doi.org/10.1176/appi.ajp.2019.18080957
Fuente: Individuals who attempt suicide carry an increased genetic liability for depression, regardless of their psychiatric disorder. https://www.eurekalert.org/pub_releases/2019-06/tmsh-iwa060519.php
Investigación original: Fernandez-Jimenez N, et al. Mendelian Randomization analysis of celiac GWAS reveals a blood expression signature with diagnostic potential in absence of gluten consumption. Hum Mol Gen. 2019. DOI: http://dx.doi.org/10.1093/hmg/ddz113
junio 7, 2019 a las 8:45 am #29741GenotipiaSuperadministradorNOTICIAS DEL VIERNES 7 DE JUNIO DE 2019
Investigaciones originales:
Papadimitriou S, et al. Predicting disease-causing variant combinations. Proc Nat Ac Sci. 2019. Doi: https://doi.org/10.1073/pnas.1815601116
Renaux A, et al. ORVAL: a novel platform for the prediction and exploration of disease-causing oligogenic variant combinations. Nuc Ac Res. 2019. Doi: https://doi.org/10.1093/nar/gkz437
Una revisión sobre los últimos avances para el tratamiento de las cegueras.
Revisión: Sahel JA, et al. Depicting brighter possibilities for treating blindness. Sci Trans Med. 2019. Doi: http://dx.doi.org/10.1126/scitranslmed.aax2324
Investigación original: Velasco S, et al. Individual brain organoids reproducibly form cell diversity of the human cerebral cortex. Nature. 2019. Doi: https://doi.org/10.1038/s41586-019-1289-x
Una revisión sobre las implicaciones clínicas y terapéuticas de las células madre del cáncer.
Investigación original: Clarke MF, et al. Clinical and Therapeutic Implications of Cancer Stem Cells. NEJM. 2019. Doi: http://dx.doi.org/10.1056/NEJMra1804280
Los órganos del cuerpo son una mezcla de células jóvenes y viejas.
Investigación original: Arrojo e Drigo, R, et al. Age Mosaicism across Multiple Scales in Adult Tissues. Cell Metabolism. 2019. DOI: http://dx.doi.org/10.1016/j.cmet.2019.05.010
Fuente: How old are your organs? To scientists’ surprise, organs are a mix of young and old cells. https://www.salk.edu/news-release/how-old-are-your-organs-to-scientists-surprise-organs-are-a-mix-of-young-and-old-cells/
Una revisión sobre las correlaciones genéticas en rasgos de enfermedades poligénicas.
Investigación original: van Rheenen W, et al. Genetic correlations of polygenic disease traits: from theory to practice. Nat Rev Gen. 2019. Doi: https://doi.org/10.1038/s41576-019-0137-z
junio 10, 2019 a las 8:56 am #29805GenotipiaSuperadministradorNOTICIAS DEL LUNES 10 DE JUNIO DE 2019
Investigación original: Iacono G, et al. Single-cell transcriptomics unveils gene regulatory network plasticity. Genome Bio. 2019. Doi: https://doi.org/10.1186/s13059-019-1713-4
Fuente: Cómo interactúan los genes para construir tejidos y organismos. https://www.crg.eu/en/news/how-genes-interact-build-tissues-and-organisms#S1
Investigación original: Ma W, et al. An Intelligent DNA Nanorobot with in Vitro Enhanced Protein Lysosomal Degradation of HER2. Nano Lett. 2019. Doi: https://doi.org/10.1021/acs.nanolett.9b01320
Fuente: DNA nanorobots target HER2-positive breast cancer cells. https://www.acs.org/content/acs/en/pressroom/newsreleases/2019/june/dna-nanorobots-target-her2-positive-breast-cancer-cells.html
Investigación original: Posner R, et al. Neuronal Small RNAs Control Behavior Transgenerationally. Cell. 2019. Doi: https://doi.org/10.1016/j.cell.2019.04.029
Investigación original: Rius R, et al. Biparental inheritance of mitochondrial DNA in humans is not a common phenomenon. Gen Med. 2019. Doi: https://doi.org/10.1038/s41436-019-0568-0
Investigación original: Timmons JA, et al. Longevity‐related molecular pathways are subject to midlife “switch” in humans. Aging Cell. 2019. Doi: https://doi.org/10.1111/acel.12970
junio 11, 2019 a las 9:23 am #29938GenotipiaSuperadministradorNOTICIAS DEL MARTES 11 DE JUNIO DE 2019
Investigación original: Vilariño-Güell C, et al. Exome sequencing in multiple sclerosis families identifies 12 candidate genes and nominates biological pathways for the genesis of disease. Plos Gen. 2019. Doi: https://doi.org/10.1371/journal.pgen.1008180
Investigación original: Hassannia B, et al. Targeting Ferroptosis to Iron Out Cancer. Cancer Cell. 2019. Doi: https://doi.org/10.1016/j.ccell.2019.04.002
Investigación original: Caffeine and the Dyskinesia Related to Mutations in the ADCY5 Gene. Ann Intern Med. 2019. Doi: http://dx.doi.org/10.7326/L19-0038
Investigación original: Dangaj D, et al. Cooperation between Constitutive and Inducible Chemokines Enables T Cell Engraftment and Immune Attack in Solid Tumors. Cancer Cell. 2019. Doi: https://doi.org/10.1016/j.ccell.2019.05.004
Investigación original: Yalcouye A, et al. A novel mutation in the GARS gene in a Malian family with Charcot‐Marie‐Tooth disease. Mol Gen Genom Med. 2019. Doi: https://doi.org/10.1002/mgg3.782
Investigación original: Zhou C, et al. Off-target RNA mutation induced by DNA base editing and its elimination by mutagenesis. Nature. 2019. Doi: https://doi.org/10.1038/s41586-019-1314-0
-
AutorEntradas
- Debes estar registrado para responder a este debate.
